Probiotic Strains for Manufacturing Industries | Unique Biotech (2023)

Our hero strains to make your brand standout

Unique Biotech Limited with its innovative technology offers probiotic strains that are stable and safe for human consumption. We have developed unique probiotic strains that are especially useful for supplementing infant milk formula with probiotics while maintaining its taste and texture.

We are pioneers in probiotic manufacturing, offering well-researched, effective, and safe probiotic strains. We are solely dedicated to manufacturing high-quality probiotics and thus have the expertise to provide the right probiotic strains that are most suited to food dietary and supplements. From vegetative cultures to spore-forming cultures, our vast repository has them all.

Our probiotic strains are well-characterized with established probiotic properties and efficacy proven through clinical studies. They survive within the gut and are resistant to stomach acid and bile. Rest assured of the viability of the strains till the end of shelf life. The trust of our customers is of paramount importance to us and we assure you of the quality, efficacy, and safety of our probiotic strains.

Features of our Probiotic Strains

  • Bile and stomach acid resistant
  • Adhesion and colonization of probiotic/ bacteria/ strains in the intestine
  • Viability till the end of the shelf life
  • Characterized and well documented
  • Zero side effects

Featured strains

Probiotic Bacillus coagulans Unique IS-2

Our flagship probiotic strain, Bacillus coagulans Unique IS-2 is a well-characterized and shelf-stable probiotic that stays in tune with the ever-changing demands of consumers in the ingredient market. Owing to its diverse health benefits, Bacillus coagulans has been added as an unparalleled ingredient in dietary supplements, functional foods, and beverages.

The health of our consumers is of utmost importance to us and therefore our Unique IS-2 has been subjected to several clinical trials to establish its safety and efficacy before making it available in the market. It is ‘the toughest when it comes to stability withstanding the harsh environment of the stomach.

Probiotic Strains for Manufacturing Industries | Unique Biotech (1)

Being naturally encapsulated with a hard shell, it survives all manufacturing processes without losing its viability making it a robust strain.

Bacillus coagulans Unique IS-2 is one of the most clinically researched probiotic strains. Its efficacy has been established in the following conditions.

  • Digestive health (diarrhoea, constipation, irritable bowel syndrome (IBS), Inflammatory bowel disease (IBD), functional abdominal pain)
  • Acute diarrhoea (antibiotic-induced, bacterial infection, diarrhoea caused by rotavirus)
  • Women's health- Bacterial vaginosis
  • Oral health
  • For healthy liver (liver cirrhosis) and heart (cholesterol reduction)
  • In the sports segment- Enhancement of protein absorption
  • Applications: drug, food supplement and as an ingredient in different foods and beverages

Dosage forms: capsules, soft gels, sachets, stick packs, effervescent/chewable tablets and gummies.

Probiotic Bacillus clausii UBBC - 07

Bacillus clausii UBBC-07 is among the well-documented and completely characterized probiotic strains that have been widely used to help in the treatment of diarrhoea. The advantage of B.clausii UBBC-07 is that it is resistant to a wide range of antibiotics and can be administered concomitantly. Being a spore-forming probiotic, Bacillus clausii is stable at room temperature and can withstand a wide range of processing conditions without losing its viability. With its long history of use, B.clausii UBBC-07 is the ideal probiotic ingredient of choice in dietary supplements, functional foods, and beverages.

Probiotic Strains for Manufacturing Industries | Unique Biotech (2)

Safety and efficacy have been established through clinical studies for the following indications:

  • Diarrhoea in children and adults
  • Helps restore microflora balance in the intestine
  • Upper respiratory tract infections (URTIs) in children
  • Inflammatory bowel disease (IBD)
  • Oral Health ( gingivitis)
  • Oral Mucositis in cancer
  • Applications: drug, food supplement and as an ingredient in different foods and beverages

Dosage forms: oral suspension, capsules, soft gels, sachets, stick packs, effervescent/chewable tablets and gummies.

Saccharomyces boulardii Unique - 28

Saccharomyces boulardii Unique 28 is a safe, well-characterized probiotic yeast. Whole-genome sequencing, preclinical studies and clinical studies have confirmed the safety of S.boulardii Unique 28.

It has been clinically proven to significantly help reduce diarrhoea, defecation frequency, and abdominal pain. In addition, it helps restore and maintain the microfloral balance in the intestine.

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Probiotic Strains for Manufacturing Industries | Unique Biotech (3)

It can be taken concomitantly with antibiotics as it is a fungus and unaffected by antibiotics, therefore particularly useful in the treatment of antibiotic-associated diarrhoea (AAD)

  • Helps reduce diarrhoea (all kinds)
  • Helps restore normal bowel function
  • Help reduce bloating and flatulence
  • Available as a bulk powder or as finished formulations in the form of capsules and sachets.

Lactobacillus salivarius UBLS-22

‍Lactobacillus salivarius UBLS-22 is a clinically proven strain aimed at improving cardiovascular health. It is a well-characterized probiotic that is isolated from human gastrointestinal tracts, human milk, and various other sources. This is one of the Lactobacillus strains that have cholesterol-lowering properties and diminishes the risk of hypercholesterolemia.

This strain reduces LDL, which is bad cholesterol and boosts the level of good cholesterol or HDL. This change in the levels of cholesterol further helps minimize the risk of developing heart diseases while ensuring the heart is functioning properly.

Probiotic Strains for Manufacturing Industries | Unique Biotech (4)

Additionally, this strain exhibits properties that lead to the production of antimicrobial compounds, discourage faecal enzymatic activity and restore protective immune response.

‍Lactobacillus salivarius also aids in reducing colonization by GI pathogens. This is a bacterial probiotic that is also known to prevent and treat various other chronic diseases as well, such as asthma, halitosis and atopic dermatitis.

  • Helps reduce low-density lipoprotein
  • Helps increase high-density lipoprotein
  • Helps reduce total cholesterol and triglycerides
  • Reduces inflammation
  • Modulates gut microbiota
  • Reduce low-density lipoprotein

Clinical study: Effect of the probiotic on serum lipids, insulin sensitivity, inflammatory markers and gut bacteria

Other Probiotic Strains

  • Lactobacillus Strains

Lactobacillus Strains are good and healthy bacteria that aid in breaking down food and absorbing nutrients. This strain often plays an integral part in those probiotics that are specifically formulated to treat diarrhoea and to give gut health a boost.

  • Bifidobacterium Strains

Bifidobacterium Strains are shelf-stable probiotics that are often added to several functional food and beverage products. Several studies have also shown the potential to treat and prevent colorectal cancer.

  • Bacillus Strains

Bacillus strains have been gaining interest for quite some time now. After undergoing multiple tests and trials, it was found that this family of strains boosts immune health and is ideal for treating constipation and diarrhoea.

  • Streptococcus Strains

Streptococcus Strains are one of the clinically proven probiotics that promote digestive health in the human body and contribute to overall immune health. The strain is also considered to be a probiotic of choice to suppress pathogen activity and diminish gut inflammation.

  • Clostridium Strains

Clostridium Strains are widely recognized to treat antibiotic-associated diarrhoea and inhibit the growth of E.Coli. It is also proven to have therapeutic effects for patients with irritable bowel disease or IBD.

  • Enterococcus Strains

Enterococcus Strains have proven effective in preventing and treating IBS or irritable bowel syndrome symptoms and other chronic intestinal diseases.







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Frequently Asked Questions(FAQs)

What do strains mean in probiotics?

Probiotic strains are genetic subtypes of species. Each probiotic strain has a different effect on the body. There are over 500 known probiotic strains. Two strains of Lactobacillus acidophilus, for instance, have over 100 different alleles, each with other functions and benefits. For example, Lactobacillus acidophilus UBLA-34 provides many health benefits specific to the intestinal tract lining, while strain B-64 has been shown to help with bloating and gas. Thus, probiotic strains are an essential part of understanding the quality of probiotics.

What are probiotic products?

What is the best probiotic product?

How many strains of probiotics are there?

Probiotic strains fall into seven main groups. These groups consist of Lactobacillus, Enterococcus, Saccharomyces, Bifidobacterium, Streptococcus, Escherichia and Bacillus. Probiotic strains within each probiotic family have different functions and benefits. However, there are more than six thousand types of probiotic bacteria strains.

It can be hard to know what to look for in each brand, especially when they all claim to be the best or look like candy. You may think it is just about brands, money and marketing, but there is a lot of information you need to know before buying your next probiotic.

What are probiotic products?

What is the best probiotic product?

What are the most common types of probiotics?

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Which probiotic strains do I need?

It is recommended to choose probiotic products with at least 1 billion colony-forming units containing the genus Lactobacillus, Bifidobacterium, Bacillus, or Saccharomyces boulardii. Here are some of the best probiotic strains and their health benefits -

  • Lactobacillus acidophilus - Fights harmful bacteria.
  • Lactobacillus fermentum - Strengthens the immune system
  • Lactobacillus casei/paracasei - Helps fight & cure inflammatory bowel diseases like cramping, abdominal pain, constipation, diarrhoea, bloating, and gas.
  • Lactobacillus plantarum - Fights disease-causing bad bacteria, boosts the digestive system and helps produce vitamins.
  • Lactobacillus reuteri. - Beneficial for female urinary tract and vaginal health; Reduces ulcer-causing bacteria; Supports heart health
  • Lactobacillus delbrueckii subsp. bulgaricus - Helps cure IBS (Irritable Bowel Syndrome)
  • Lactobacillus rhamnosus - Improved gut health, and fights cavities
  • Bifidobacterium longum ssp. longum. - This bacterial strain protects from intestinal infections, colon cancer, inflammatory bowel diseases and can even cure depression.
  • Bifidobacterium longum ssp. infantis. - Helps cure lactose intolerance, vaginal yeast infections, eczema, and urinary tract infections.
  • Bifidobacterium bifidum. - Helps prevent IBS and maintain the immune system
  • Bifidobacterium animalis ssp. Lactis. - This probiotic strain is said to stimulate vitamin production and prevent infection.

What are probiotic products?

What is the best probiotic product?

What are the most common types of probiotics?

Why are Probiotic Strains Beneficial?

When you have harmful bacteria inside you, you can get sick often and worse as such conditions can cause a great deal of pain and inflammation. Probiotic strains are good bacteria that help your body fight off infections and diseases that can cause a great deal of pain and inflammation. These probiotic strains fight off the harmful bacteria naturally in your system.

The question of which strains to choose (or whether to choose a strain at all) comes up all the time. If you are doing a gut-healing protocol, should you take Lactobacillus strains like acidophilus and Bifidus? On the other hand, if you are suffering from an upper respiratory infection (such as sinusitis), should you consider Streptococcus thermophilus or Bacillus clausii. These few strains have been shown to reduce upper respiratory infections? Yes, probiotics can help you cure your condition. However, we recommend talking to your healthcare professional before randomly buying probiotic supplements.

What are probiotic products?

What is the best probiotic product?

What are the most common types of probiotics?

(Video) It’s about the Metabolome of the Microbiome: It’s Not About the CFU!

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What is the most effective probiotic strain? ›

There are two genus that are the most popular and have been proven to provide health benefits for certain people effectively: Lactobacillus and Bifidobacterium. Most probiotics will include strains from these two genera.

How many strains is best in a probiotic? ›

Generally speaking, a multi-strain probiotic can be a good option as an everyday supplement to support gut health. Most high-quality, multi-strain probiotics contain around 5 or 6 different strains, but why not 10 or 15 strains?

How many strains of probiotics are there? ›

Common Types of Probiotics. There are more than 500 different kinds of probiotic species, according to Harvard Medical School. Each probiotic is identified by its unique strain, which is named first by its genus, then by the species, and then by their strain (e.g. Lactobacillus casei W56).

How do I choose a probiotic strain? ›

Summary. To choose the best commercial probiotic supplement, look for one that contains at least 5 CFUs, multiple strains like Lactobacillus and Bifidobacterium, is dairy-free, and contains no binders and fillers like lactose or cornstarch.

What are the 3 types of probiotics? ›

While there are 1000s of specific probiotic species, there are really only three different types of probiotics.
Only 3 Main Types of Probiotics
  • Lactobacillus and Bifidobacterium Blends.
  • Saccharomyces boulardii, a beneficial yeast.
  • Soil-Based Blends, usually Bacillus species.
Apr 27, 2019

Which probiotic strain is best for immune system? ›

Probiotics may help a healthy immune system

The L. CASEI 431®, BB-12® and LGG® strains have all been studied in high-quality clinical studies. In children and adults, supplementing with these strains has been associated with a promotion of the immune system and may lower incidence of respiratory and flu-like sickness.

Can you take two different strains of probiotics? ›

It's absolutely OK to take multiple probiotic supplements at the same time, says Singh. But you may want to look into trying supplements with different strains to target various needs within the gut. * Otherwise, taking just one multistrain probiotic supplement will serve the same purpose.

What is the #1 probiotic? ›

The probiotic strain in Culturelle® - Lactobacillus rhamnosus GG (LGG®) – is the #1 most clinically studied strain of probiotic. Considered the premier probiotic in the world, over 1,000 scientific studies and over 30 years of research have demonstrated the safety and efficacy of Lactobacillus rhamnosus GG (LGG®).

What does strains mean in probiotics? ›

Strain: The individual bacteria strain determines the health benefits you should expect from the probiotic. Proof: Any claims about health benefits should be backed up by scientific studies on that product and the probiotic strain in it.

What is important in a probiotic? ›

Probiotics are made up of good bacteria that helps keep your body healthy and working well. This good bacteria helps you in many ways, including fighting off bad bacteria when you have too much of it, helping you feel better. Probiotics are part of a larger picture concerning bacteria and your body — your microbiome.

What are the four main families of probiotics? ›

There are four main families of probiotics: Lactobacillus and Bifidobacterium provide the most commonly used good bacteria, while others belong to the Saccharomyces (actually yeasts, a different type of microorganism) and Streptococcus groups.

What are probiotics examples? ›

The most commonly used probiotic strains include the lactic acid bacteria (LAB), Gram-positive microbes that have been used for centuries in food production processes (yogurt, cheese, pickles).

How do you know if a probiotic is good? ›

Signs of effective probiotics include:
  1. Regular bowel movement. Probiotic supplementation can ease bowel movement and reduce belching, bloating, and general abdominal fullness. ...
  2. Less digestive discomfort. ...
  3. Improved mood. ...
  4. Weight loss. ...
  5. Improved glycemic index and cholesterol levels.
Apr 28, 2020

What are the signs that probiotics are working? ›

But there are some common indicators that they may be working for you.
  • Less stomach pain. For some people, certain probiotics can help with stomach pain and cramps. ...
  • More frequent poops. ...
  • Less bloating. ...
  • Improved sleep. ...
  • Better mood, memory, and mental clarity. ...
  • Fewer vaginal infections.
Jul 20, 2022

What is the best probiotic strain for diarrhea? ›

Lactobacillus rhamnosus GG, Saccharomyces boulardii, Bifidobacterium lactis, and Lactobacillus casei are some of the most effective strains of probiotics for treating diarrhea.

What is the #1 probiotic? ›

The probiotic strain in Culturelle® - Lactobacillus rhamnosus GG (LGG®) – is the #1 most clinically studied strain of probiotic. Considered the premier probiotic in the world, over 1,000 scientific studies and over 30 years of research have demonstrated the safety and efficacy of Lactobacillus rhamnosus GG (LGG®).

Is it better to have more strains in probiotics? ›

Are Multiple Strains Better When Choosing a Probiotic? No, the number of strains does not determine if one probiotic is better than another. Some probiotic brands offer products with multiple strains of bacteria with the rationale that this may replicate the normal environment of the gut.

What is the best probiotic recommended by gastroenterologists? ›

What is Align, the #1 Doctor and Gastroenterologist Recommended Probiotic Brand? Align Digestive Support Probiotic Supplement contains Bifidobacterium 35624™, a strain of probiotic that has been researched for over 20 years.


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